Pipeline

We take aim at the world’s most intractable diseases. Our portfolio spans both novel and known (but traditionally undruggable) targets.

Indication

rModality

Target

Discovery

Pre-clinical

Clinical

IL-2

Cancer

Metabolic

Immunity

Cancer

Auto-immune

Alzeimer's disease

MYC

Inframmation

Auto-immune

SM

Inframmation

Auto-immune

SM

SM

SM

SM

IL-1β

IL-1β

SM

IL-1α

PTPN2

Cancer

Auto-immune

Inframmation

Auto-immune

ALS

Alzeimer's disease

ALS 1

Alzeimer's disease

IL-1RA

SM

ASO

FLCN

FLCN

Unless otherwise indicated, the rModality is a small molecule
‍rModality = RNA-targeted modality